Sunday, November 15, 2009

Bio note

Definition
- DNA has a repeating, antiparallel helical structure formed by complementary base pairing of nucleotides proposed by Watson and Crick
- AT/GC rule is explained purines (A and G) always bond with pyrimidines (T and C)
- original DNA strands are used as templates for the synthesis of new DNA strands.
- semiconservative mechanism is half parental strand and half new strand

http://www.youtube.com/watch?v=teV62zrm2Po
Origin of replication is a site within a chromosome that serves as a starting pooint for DNA
Begininig, two DNA strands unwind. Replication process is start with primer and new DNA is made in the 5' to 3' direction.
Nucleotides bind to parental strands according to the AT/GC rule and are linked together to form daughter strands.
Process continuesssssssssssssssss......
until produce 2 double helices with the same base sequence.
Leading strand is synthesis of the leading strand begins in the direction of the replication fork.
Lagging strand is made as a series of small fregments that areentually cinnected to each to form a continues strand.
Okazaki fragment is a short fragment of DNA create on lagging strand during the replication process
http://en.wikipedia.org/wiki/Okazaki.fragment


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